Research has indicated that one in every five men experiences the symptoms of premature ejaculation at one or another point in their life.
As we all know, neither men nor their partners are happy in a situation where they ejaculate within a minute or less during sexual intercourse.
Most of the counsellors and sexologists unanimously agree that men experiencing Premature ejaculation (PE) are unable to have a happy sex life.
It often leads to frustration or even depression in men and their partners, making them seek medical treatments and go on a lookout for a wonder drug.
While medical sciences provide numerous options and pills to treat erectile dysfunction (ED), the treatment for PE may or may not be similar.
Let us understand more about the available pills for premature ejaculation and if they work.
The article is a part of our comprehensive series of blogs on “Premature Ejaculation”.
How do premature ejaculation pills work?
The core reason for premature ejaculation is different for different people. However, the symptoms might be the same.
Thus there is no one fit solution to treat PE in all men.
When it comes to treating premature ejaculation, the most commonly used drugs belong to the SSRIs category like Sertraline (brand name Zoloft).
These were initially formulated to treat specific psychological conditions like depression, anxiety, mood swings, etc. However, for men, delayed orgasm or ejaculation, which is actually a side effect of these drugs, comes as a benefit.
Various pieces of research have confirmed that these medications have a positive impact on improving sexual performance and delaying ejaculation. Many of these drugs are used as an off label treatment to enhance sexual stamina and delay ejaculation.
Let’s be realistic and accept that there is no single pill to improve all the aspects of your sexual performance. While specific medication helps to effectively address particular issues of premature ejaculation, others can be pretty difficult to handle if the problem is too complex.

How do SSRIs treat premature ejaculation?
These are a particular class of medications that are developed to treat depression.
Once consumed the drug helps to improve the amount of serotonin in your brain, reducing the symptom of depression.
However, SSRIs have a considerable side effect, which is considered a great boon by many men suffering from PE.
Yes, you have guessed it right. The main side effect is that SSRIs significantly increase the effort and time taken to reach orgasm during sexual intercourse. Thus SSRIs can be effectively used to treat the symptoms of premature ejaculation.
One of the commonly used drugs in the SSRIs category is sertraline.
Research has given clear cut evidence that if used daily, sertraline and other SSRI drugs can considerably improve the symptoms of PE.
In a study conducted in 1998, men with PE were given a daily dosage of sertraline(25mg). Gradually it was increased to 50mg and finally to 100mg.
The results- mean delay time improved from 1 minute to 13.1 minutes.
Read more in our article on “Sertraline for premature ejaculation”.
Premature ejaculation pills
Scientists have developed several PE pills to help men last longer before they orgasm and ejaculate.
Here are some of the best medications for treating various sexual performance issues, including premature ejaculation.
ED medications
At present, the most effective pills are PDE5 inhibitors and are commonly used for treating ED and improving your erections. This normally helps if premature ejaculation is associated with erectile dysfunction.
These medications work by improving the effectiveness of the PDE5 enzyme found in the arteries supplying blood to the penis region. This will help to enhance the blood flow to your penis, making it easier to maintain erection and improving the ejaculatory time.
Following are some popularly used ED medications:
- Sildenafil(Viagra)
- Tadalafil (Cialis)
- Vardenafil (Levitra)
Check out other similar medication options for premature ejaculation here!
Bottom Line
As there are innumerable reasons for premature ejaculation, finding the exact cause will help you discover the correct treatment option as well as the pill that works for you.
As mentioned in this article, the most commonly used treatment option/pills are SSRIs. However, depending on the issue, your doctor will also prescribe you a specific combination of PE medication.
You need to understand one thing that neglecting your PE will only worsen the issue. Proper medical intervention can help you to get the best treatment method and ensure a smooth recovery.

Click here to talk discreetly with a medical practitioner, discuss your issues from the comforts of your home and get suitable treatment plans.