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Paxil (Paroxetine) for Premature Ejaculation: Does it Work?

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There is no doubt that antidepressant medications play a vital role in helping people cope with their mood swings.

But do you know that they are also highly helpful in treating sexual dysfunction?

Research done by several reputed organisations across the globe has brought forth convincing evidence to suggest the effectiveness of these medications in treating various sexual dysfunction.

One such medication is Paxil.

The article is a part of our comprehensive series of blogs on “Premature Ejaculation.

What is Paxil?

This is an antidepressant that belongs to a specific category of drugs called SSR/s or selective serotonin reuptake inhibitors.

People who are suffering from mental health issues have unbalanced chemicals in their brains. 

Paxil is prescribed to balance the brain chemicals and treat these mental health issues such as:

  • Depression
  • Anxiety
  • PTSD
  • Panic attacks
  • Obsessive-compulsive disorder(OCD)
  • Premenstrual dysphoric disorder(PMDD), etc.
Anxiety

This drug is available in liquid and tablet form and should be taken orally.

Like all antidepressant medications, people who take Paxil may experience specific side effects such as sweating, drowsiness, fluctuation in their appetite, constipation, weight gain, dizziness etc.

But there is something more that Paxil has to offer.

Paxil is prescribed as an off label treatment for treating premature ejaculation.

How does Paxil help with premature ejaculation?

Serotonin is undoubtedly a very important hormone in the human brain responsible for happiness, creating a feeling of well-being and stabilising the mood.

In addition, this hormone also plays a crucial role in digestion, bowel movement and eating.

Drugs belonging to the SSRIs category prevent the reduction of serotonin.

They work by actively blocking presynaptic membrane 5-HT transporters, inhibiting serotonin (5-HT) breakdown and reuptake. 

This will result in higher availability of serotonin in the synaptic clefts.

The abundant availability of serotonin smoothens the way for its binding to 5-HT receptors, delaying the time for ejaculation.

A randomised, single-blind study conducted on 100 participants in 2007 with three different SSRIs has indicated a significant increase in their AIPE score (Arabic Index of Premature Ejaculation).

A systematic review of studies consisting 500 “unique articles”   has indicated that Paxil is more effective in increasing the ejaculatory time compared to other SSRIs such as Lexapro and Prozac.

How to take Paxil for PE?

Paxil should be taken strictly as per the instruction of your doctor. Ensure that you read the medication guidelines in the instruction sheets.

If you are consuming an oral tablet, swallow it as a whole without chewing or crushing. For easy absorption, drink a large glass of water along with the pill.

On the other hand, if you are on oral suspension, carefully measure the dosage with the help of a measuring device or syringe provided.

How long does Paxil take to work for premature ejaculation?

For a visible reduction in the symptoms, it can take up to 4-5 weeks, continuing the medication without fail.

Never stop the medication immediately, as you could experience withdrawal symptoms. Instead, ask your doctor how to taper off your dosage.

Side effects of Paxil for premature ejaculation (Efficacy and safety)

Paxil is generally safe for most people. However, some people experience side effects.

Common side effects

  • Headache
  • General tiredness
  • Nausea
  • Diarrhoea
  • Sleeping difficulties etc.

In most cases, typical side effects will wear off as your system gradually adjusts to the new medication.

Serious side effects

This is extremely rare and occurs in 1 out of a thousand people. Some of the severe side effects include:

  • A painful erection lasting for more than 4 hours
  • Shortness of breath
  • Chest pain
  • Nose bleeds
  • Suicidal tendency
  • Blurred vision
  • Restlessness

In sporadic cases, it is possible to have anaphylaxis(severe allergic reaction) to paroxetine.

If you are experiencing any of the severe side effects after consuming paroxetine, immediately seek medical help.

Check out other similar medication options for premature ejaculation here!

Concluding Words

Premature ejaculation can be pretty stressful, especially in your younger years. This problem can worsen if you do not get treatment at the right time. Seek expert medical attention as soon as you or your partner feels that you might be having this issue.

Since its launch, Paxil has become the best bedroom pal for thousands of men. However, as everyone’s biochemistry is unique, the results may vary.

Along with this medication, it is better to follow a holistic approach focussing on regular exercise, medication and a good work-life balance.

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